Table 1

Effect of PER 2 and CRY 2 on the cell cycle of MCF-7 cells


G1
S
G2/M

GFP
7414
15.57
10.29
pCS2
65.36
18.03
16.61
PER2
82.24
7.16
10.60
pCS2 + pcDNA3.1
62.61
17.49
19.90
PER2 + CRY2
89.19
0.58
10.22

Cell cycle analyses were conducted on parental, vector-transfected, PER 2 overexpressing MCF-7 cells, CRY 2 overexpressing MCF-7 cells, and cells over expressing both PER 2 and CRY 2. After three days of expression, propidium iodide(PI) staining and samples were analyzed by flow cytometry.

Xiang et al. Journal of Circadian Rhythms 2008 6:4   doi:10.1186/1740-3391-6-4