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Geomagnetic/Geographic Differences among Cycles with Periods in the Range of 0.8 – 2.0 years Characterizing the Incidence of Sudden Cardiac Death and Myocardial Infarction |
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| Sudden Cardiac Death (SCD)1* |
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| Site |
Span |
T, Δt, N |
SC (N) |
Period (y) |
(95%CI) |
Amplitude |
(95%CI) |
A(% MESOR) |
P-value2 |
|
|
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| Transyear (TY) or Candidate Transyear (cTY) Detected |
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| Minnesota |
1999–2003 |
5 y, 1 d, 1826 |
343 |
1.392 (TY) |
(1.173, 1.611) |
0.042 |
(0.00, 0.09) |
22.0 |
0.014 |
| Arkansas |
1999–2003 |
5 y, 1 d, 1826 |
273 |
1.095 |
(0.939, 1.251) |
0.032 |
(0.00, 0.07) |
21.1 |
0.040 |
| 1.686 (cTY) |
(1.293, 2.071) |
0.031 |
(0.00, 0.07) |
20.7 |
0.044 |
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| Czech Rep. |
1999–2003 |
5 y, 1 d, 1826 |
1006 |
0.974 |
(0.856, 1.091) |
0.078 |
(0.00, 0.16) |
14.2 |
0.007 |
| 1.759 (cTY) |
(1.408, 2.110) |
0.077 |
(0.00, 0.15) |
13.9 |
0.010 |
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| 1994–2003 |
10 y, 1 d, 3652 |
1792 |
1.726 (TY) |
(1.605, 1.848) |
0.074 |
(0.02, 0.13) |
15.1 |
<0.001 |
|
| 1.000 |
(0.944, 1.056) |
0.052 |
(0.00, 0.10) |
10.6 |
0.010 |
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| Candidate Transyear Not Detected |
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| North Carolina |
1999–2003 |
5 y, 1 d, 1826 |
752 |
0.929 |
(0.834, 1.023) |
0.069 |
(0.00, 0.14) |
16.9 |
0.007 |
| Tbilisi, Georgia |
Nov'99–2003 |
4.1 y, 1 d, 1505 |
130 |
0.988 |
(0.862, 1.114) |
0.035 |
(0.00, 0.07) |
40.7 |
0.007 |
| Hong Kong |
2001–2003 |
3 y, 1 m, 36 |
52 |
0.843 |
(0.651, 1.036) |
0.022 |
(NS) |
44.9 |
0.077 |
|
|
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| Myocardial Infarction (MI) |
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| Site |
Span |
T, Δt, N |
MI (N) |
Period (y) |
(95%CI) |
Amplitude |
(95%CI) |
A(% MESOR) |
P-value2 |
|
|
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| Coexisting Year (Circannual) and Transyear (TY) |
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| Czech Rep. |
1999–2003 |
5 y, 1 d, 1826 |
52598 |
1.014 |
(0.989, 1.038) |
2.85 |
(2.22, 3.48) |
9.88 |
<0.001 |
| 1.354 (TY) |
(1.252, 1.456) |
1.35 |
(0.69, 2.02) |
4.68 |
<0.001 |
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| 1994–2003 |
10 y, 1 d, 3652 |
115520 |
0.998 |
(0.988, 1.009) |
3.03 |
(2.47, 3.60) |
9.58 |
<0.001 |
|
| 1.453 (TY) |
(1.417, 1.489) |
1.91 |
(1.34, 2.49) |
6.04 |
<0.001 |
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| 1.15 (TY) |
(1.116, 1.184) |
1.23 |
(0.64, 1.82) |
3.88 |
<0.001 |
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* With focus on transyears with periods longer than 1.0 year. 1International Classification of Disease (ICD10) Code I46.1, excluding MI and sudden death of unknown or unspecified cause (except before 1999). T: Length of data series (y = years); Δt: sampling interval (d = day, m = month); N: number of data (including 0s). Period and 95% confidence interval (CI) estimated by nonlinear least squares. In longer (10-y) series, a neartransyear (cycle with a period between 1.0 and 1.2 y) is detected for MIs in addition to a fartransyear. Brevity of series and lack of ordering statistical significance qualify results from Hong Kong. Note that transyears are found in 3 of 6 locations (P < 0.05 by linear least squares) with a relative amplitude >12 (% of MESOR). 2From linear least squares analysis, not corrected for multiple testing. Amplitude expressed in N/day.[62] | |||||||||
Halberg et al. Journal of Circadian Rhythms 2005 3:2 doi:10.1186/1740-3391-3-2 |
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