Figure 5.

Effect of food restriction on circulating eosinophils in mice. *After log10-transformation of data expressed as percentage of mean. **To reveal the difficulty to resolve differences by the naked eye alone, and the even greater difficulty of quantifying the patterns of each group and any inter-group differences. There is a need to cover the 24-hour time scale to look for intergroup differences in the face of a large variability, what the active Claude Bernard rightly called the "extreme variability of the internal environment" [264]. Our analysis of variance reveals statistically significant time and group effects and interaction in this time-macroscopic approach, shown elsewhere [303].

Halberg et al. Journal of Circadian Rhythms 2003 1:2   doi:10.1186/1740-3391-1-2
Download authors' original image