Research

Relationship between daylength and suicide in Finland

Laura Hiltunen1
Kirsi Suominen12
Jouko Lonnqvist13
Timo Partonen1
  1. National Institute for Health and Welfare, Department of Mental Health and Substance Abuse Services, P.O. Box 30 (Mannerheimintie 166), FI-00271 Helsinki, Finland
  2. Helsinki University Central Hospital, Jorvi Hospital, Department of Psychiatry, Espoo, Finland
  3. University of Helsinki, Department of Psychiatry, Helsinki, Finland

Abstract

Background

Many previous studies have documented seasonal variation in suicides globally. We re-assessed the seasonal variation of suicides in Finland and tried to relate it to the seasonal variation in daylength and ambient temperature and in the discrepancy between local time and solar time.

Methods

The daily data of all suicides from 1969 to 2003 in Finland (N = 43,393) were available. The calendar year was divided into twelve periods according to the length of daylight and the routinely changing time difference between sun time and official time. The daily mean of suicide mortality was calculated for each of these periods and the 95% confidence intervals of the daily means were used to evaluate the statistical significance of the means. In addition, daily changes in sunshine hours and mean temperature were compared to the daily means of suicide mortality in two locations during these afore mentioned periods.

Results

A significant peak of the daily mean value of suicide mortality occurred in Finland between May 15th and July 25th, a period that lies symmetrically around the solstice. Concerning the suicide mortality among men in the northern location (Oulu), the peak was postponed as compared with the southern location (Helsinki). The daily variation in temperature or in sunshine did not have significant association with suicide mortality in these two locations.

Conclusions

The period with the longest length of the day associated with the increased suicide mortality. Furthermore, since the peak of suicide mortality seems to manifest later during the year in the north, some other physical or biological signals, besides the variation in daylight, may be involved. In order to have novel means for suicide prevention, the assessment of susceptibility to the circadian misalignment might help.


Keywords: circadian clock, suicide, light-dark transition, sunshine, temperature.

Background

Current data on the routinely occurring peaks of deaths from suicide are conflicting [1,2]. However, for the past four decades in Finland, the seasonal pattern has been stronger the lower the suicide mortality has been [3]. There is a clear peak of suicide occurrence around May or June [4-7] and a preceding peak in suicide attempts around April [8]. Furthermore, another smaller peak of suicide occurrence exists around October [7,9]. These two mortality peaks, being similar and more robust the further away the country locates from the equator, have been explained by socio-demographic and socio-economic factors [10], but since this seasonal pattern has existed for decades [11], if not centuries [12], biological factors are likely.

Major depressive episodes are known to contribute to suicide substantially [13,14], and a history of mood disorders and psychiatric hospitalization associates clearly with the seasonal occurrence of suicides [15,16]. Desynchronization of physiological rhythms, e.g. desynchronization of the circadian rhythm of core body temperature with the sleep-wake cycle [17-19] and some clock gene variants [20,21], can be associated with mood disorders. Based on our earlier psychological autopsy studies of death from suicide [22] and the data from the nationwide suicide program in Finland [23], we hypothesized that the circadian misalignment among the depressed may increase during spring, and thereby predispose to suicidal behaviors [24].

Rest-activity cycles during the day [25] and sleep stages at night [26] are controlled by circadian clocks, but they are frequently disturbed among the depressed. Furthermore, the principal circadian clock entrains to the sun light [27-29], by tracking the daily changes in rise and set times of the sun and the variation in the length of the day [30-32]. Thus, the timing of light exposure is relevant to entrainment and influences the course of mood disorders [33,34]. Therefore, we hypothesized that it is the key to the suicide mortality peaks whether the light-dark transitions give the principal circadian pacemaker a signal to accelerate or decelerate, especially among the depressed. In addition, since sunshine and ambient temperature are potential time-givers, modulate the function of biological clocks [35], and associate with deaths from suicide [3,36], we aimed to test their effect, as well.

Methods

Statistics Finland http://www.stat.fi provided us with the daily data of 43,393 suicides, 33,993 of men and 9400 (22%) of women, committed in Finland during the 35-year period of 1969 to 2003 (Tables 1 and 2). Two phenomena, which affect the timing and the speed of the light-dark transitions regularly each year, were selected a priori as the potential factors that might challenge the biological clocks and produce circadian misalignment. First, we focused on the length of the photoperiod, because at high to temperate latitudes around spring and fall equinoxes the transitions between day and night are most rapid and the durations of twilight short, as a consequence of the rotation of the earth. Second, we focused on the constant mismatch between the sun time (hereafter ST) and the coordinated universal time (hereafter UCT), arising from the earth's tilt and elliptical orbit around the sun.

OuluHelsinkiFinland
YearMenSper
100
000
MenSper
100
000
MenSper
100
000

196942 4471125.92272 32111040.392 230 21785038.11
197041 4121331.39266 17410840.582 219 98576334.37
197142 7981125.70271 39311743.112 234 03778134.96
197243 4362250.65275 37813247.932 249 05187438.86
197344 1272761.19277 20510939.322 262 14284937.53
197445 0822248.80278 48513147.042 273 81592140.51
197545 8152248.02278 62812845.402 282 11592440.49
197646 0692962.95278 69315254.542 286 39296742.29
197746 4442247.37277 97815455.402 295 66896241.91
197846 6091327.89277 73515656.172 300 79096341.86
197946 5331838.68278 56913347.742 306 78493540.53
198046 7792451.31279 45614551.892 314 84396241.56
198147 3432144.36280 58015153.822 327 47390438.84
198248 1791837.36282 75113447.392 342 86990538.63
198348 3312551.73284 56513045.682 357 17293839.79
198448 6202551.42286 09214952.082 369 22898841.70
198549 0652346.88287 85811339.262 377 78096440.54
198649 4053060.72290 37014951.312 385 866102342.88
198749 8902856.12292 93513746.772 392 868106844.63
198850 1384487.76294 24215050.982 401 368111246.31
198950 9512956.92295 66516054.122 412 760112146.46
199051 6233363.93298 42019866.352 426 204119949.42
199152 2543566.98302 60918561.142 443 042119348.83
199252 9593667.98306 29820466.602 457 282116047.21
199353 4953565.43311 13417255.282 470 196111245.02
199454 6612342.08316 36717655.632 481 649108043.52
199556 1322646.32322 07417955.582 491 701108143.38
199657 4362645.27327 16813140.042 500 59696638.63
199758 4823661.56332 11315847.572 509 098103941.41
199859 6062643.62337 29712135.872 516 07596538.35
199961 0254065.55341 12513940.752 523 02696138.09
200062 8002844.59344 52014341.512 529 34187934.75
200164 1163148.35347 92515043.112 537 59793636.89
200264 9952233.85349 12113939.812 544 91682532.42
200365 9652943.96350 33411933.972 552 89382332.24

Table 1

Men's suicides in numbers during the study period

The yearly male population, number of suicides(S), and suicide mortality for men in Oulu, Helsinki, and Finland from 1969 to 2003.

OuluHelsinkiFinland
YearWomenSper
100
000
WomenSper
100
000
WomenSper
100
000

196946 245510.81333 5024312.892 384 06024610.32
197045 65648.76325 0345817.842 378 3512209.25
197146 474510.76330 2055817.572 391 8752229.28
197247 633510.50333 5075717.092 404 3502399.94
197348 302612.42335 6876017.872 416 61924910.30
197449 2721122.33337 4704713.932 428 57225510.50
197550 13259.97337 5707221.332 438 37725410.42
197650 4101223.81336 9806619.592 444 44425310.35
197750 691815.78335 0575416.122 451 29925810.53
197850 9641121.58334 5475315.842 457 2982379.65
197951 188611.72334 9816017.912 464 5082429.82
198051 58247.76335 6306318.772 472 93526410.68
198152 23711.91336 5115616.642 484 6772399.62
198253 0591018.85338 1165917.452 498 84626710.69
198353 225611.27339 1085616.512 512 6862499.91
198453 44335.61340 1625415.882 524 52025310.02
198553 97647.41341 7815816.972 532 8842499.83
198654 3491222.08343 5765315.432 539 77828711.30
198754 7601018.26346 1626518.782 545 73430111.82
198855 125916.33346 8806217.872 552 99129611.59
198955 810814.33347 2265816.702 561 62329712.59
199056 294814.21348 9139025.792 572 27432411.60
199156 735814.10352 2077421.012 585 96030611.83
199257 391610.46354 4297721.732 597 70029711.43
199357 765610.39358 5577220.082 607 71629311.24
199458 7811220.42363 7747721.172 617 10530711.73
199560 1861219.94369 4376517.592 625 12530911.77
199661 447813.02373 6636918.472 631 72428210.72
199762 4391117.62378 5476817.962 638 25128410.77
199863 4541117.34382 8805714.892 643 57126810.14
199964 5161320.15386 3846817.602 648 2762549.59
200066 1491116.63389 4256616.952 651 77429211.01
200167 584913.32391 6496215.832 657 30427110.20
200268 2971116.11392 4854812.232 661 37927510.33
200368 878710.16393 0355513.992 666 8392619.79

Table 2

Women's suicides in numbers during the study period

The yearly female population, number of suicides(S), and suicide mortality for women in Oulu, Helsinki, and Finland from 1969 to 2003.

The nominal calendar year was split into twelve periods according to these two phenomena; first into four astronomical seasons, which are determined by spring and fall equinoxes and summer and winter solstices (for the definition, see http://asa.nao.rl.ac.uk/), and second into eight periods, by the equation of time (for the definition, see http://www.nmm.ac.uk/explore/astronomy-and-time/time-facts/the-equation-of-time), as follows (see also Figure 1). From February 11th to May 14th (hereafter marked as X1) and from July 26th to November 3rd (X2) ST goes fast compared with UCT and in between those periods, that is, from May 15th to July 25th (Y1) and from November 4th to February 10th (Y2) it goes slow. Furthermore, another categorization was made based on the equation of time separating periods when ST is either ahead or behind the UCT. In other words, ST is constantly ahead of the UCT, from April 15th to June 13th (A1) and from September 1st to December 25th (A2), and constantly behind the UCT, from June 14th to August 31st (D1), and from December 26th to April 14th (D2). Hence, ST deviates from UCT constantly and is maximally behind at February 11th (approximately 14 minutes) and vice versa maximally ahead at November 3rd (approximately 16 minutes). The Almanac Office at the University of Helsinki http://almanakka.helsinki.fi/ both provided the dates for the astronomical seasons and calculated the dates for the periods (X1, Y1, X2, Y2) of the equation of time, as well as the dates for the periods (A1, D1, A2, D2) through the whole study period.

Figure 1 

Periods according to time of equation and astronomical seasons. During X1(February 11-May 04) and X2 (July 26-November 03) (marked with pink lines) sun time is accelerating, and during Y1 (May 15-July25) and Y2 (November 04-February 10) (marked with green lines) it is decelerating compared with the coordinated universal time (UCT). During A1 (April 15-June13) and A2 (September 01-December 25) sun time stays ahead and during D1 (June 14-August 31) and D2 (December 26-April 14) it stays behind the UCT. Astronomical seasons are separated with dotted vertical lines. During astronomical spring and summer daylight exceeds darkness, and vice versa during astronomical fall and winter darkness exceeds daylight in Finland. Y-axis on the left side presents the time difference (in minutes) that sun time deviates from the UCT.


To evaluate the effect of daily sunshine hours and temperature on suicide mortality, we focused on two cities on a similar longitude but with dissimilar photoperiod: first, Helsinki (60°9.7'N, 24°57.3'E), which is the capital of Finland in the south, and second, Oulu (65°1.0'N, 25°30.0'E), which is a central city of the northern part of the country, 600 km north from Helsinki. In Helsinki 5062 suicides were committed by men, and 2160 by women, whereas 903 by men and 278 by women in Oulu. The Finnish Meteorological Institute http://www.fmi.fi/ provided us with the daily data on sunshine hours and temperature, measured within the 25-km radius from these cities throughout the study period. For the day to day analysis, the daily sunshine, measured in minutes per day, (hereafter S) and the daily temperature, measured in degrees in Celsius and averaged as the daily mean value, (hereafter T) were compared with those on the previous day and changes were marked as (+) indicating an increase, and (-) indicating a decrease from the previous day. Thus, we ended with four types of days according to weather changes, coded as T+S+, T+S-, T-S+, and T-S-, concerning the data from Helsinki and Oulu regions.

In order to take into account the differences in the yearly population sizes within and between Helsinki and Oulu, the daily means of suicides were calculated into daily means of suicide mortality rates (suicides per 100,000), for men and women, per each year, and for both cities (Tables 1 and 2). Furthermore, in order to control for the different lengths of each period studied, and to avoid the bias of having dominance of certain type of weather changes within any period of the year, the daily mean of suicide mortalities (number of suicides per day, with 95% confidence intervals [CIs]) was calculated for each period in separate (Tables 3, 4, and 5).

AreaSelected DaysAstronomical season

WinterSpringSummerFall
MFinlandAll.099
.094-.103
.120
.115-.125
.117
.112-.122
.106
.101-.111
HelsinkiAll.128
.120-.136
.138
.128-.148
.135
.123-.147
.131
.122-.140
T+S+.123
.099-.146
.135
.122-.147
.139
.122-.156
.137
.120-.155
S-.113
.092-.134
.144
.125-.163
.142
.120-.164
.115
.099-.132
T-S+.122
.108-.136
.146
.128-.163
.130
.117-.143
.133
.118-.147
S-.122
.097-.146
.140
.120-.161
.129
.112-.146
.144
.116-.172
OuluAll.119
.098-.140
.141
.123-.160
.159
.138-.180
.131
.113-.150
T+S+.107
.050-.163
.134
.103-.165
.162
.112-.212
.152
.077-.227
S-.097
.059-.135
.126
.082-.170
.175
.132-.217
.147
.101-.193
T-S+.124
.094-.154
.167
.132-.203
.156
.115-.197
.117
.073-.161
S-.097
.045-.148
.138
.110-.166
.132
.086-.178
.144
.083-.205
WFinlandAll.025
.023-.027
.031
.030-.032
.029
.028-.031
.028
.027-030
HelsinkiAll.046
.042-.050
.050
.045-.054
.049
.045-.054
.048
.043-.053
T+S+.038
.028-.048
.056
.046-.065
.049
.039-.058
.056
.043-.069
S-.051
.033-.069
.049
.041-.056
.046
.034-.058
.052
.042-.062
T-S+.042
.036-.049
.046
.034-.057
.049
.040-.057
.049
.039-.059
S-.052
.039-.065
.052
.042-.062
.051
.041-.061
.045
.031-.059
OuluAll.036
.029-.044
.040
.030-.049
.042
.032-.051
.039
.029-.048
T+S+.032
.006-.058
.031
.016-.046
.042
.023-.061
.049
.013-.086
S-.037
.015-.058
.030
.015-.043
.047
.020-.074
.020
.005-.036
T-S+.041
.019-.063
.051
.028-.074
.037
.019-.055
.043
.019-.067
S-.028
.000-.055
.045
.020-.069
.042
.020-.063
.047
.018-.076

Table 3

Astronomical seasons and men's (M) and women's (W) suicide mortality

Daily mean of suicide mortality and confidence interval of the mean in aggregate over the years from 1969 to 2003 for men and women, during astronomical seasons in Finland, Helsinki and Oulu, and according to daily changes (+/-) in temperature (T) and sunshine hours(S) in Helsinki and Oulu.

Winter: 21.12-20.03

Spring: 21.03-20.06

Summer: 21.06-22.09

Fall: 23.09-20.12

AreaSelected DaysPeriods of time of equation

X1Y1X2Y2
MFinlandAll.109
.105-.114
.124
.118-.129
.112
.107-.116
.101
.096-.106
HelsinkiAll.131
.121-.141
.142
.130-.154
.130
.122-.139
.130
.120-.140
T+S+.139
.116-.161
.149
.131-.167
.122
.097-.147
.124
.097-.151
S-.151
.123-.179
.145
.119-.170
.124
.103-.145
.110
.088-.131
T-S+.152
.122-.182
.126
.100-.153
.135
.121-.150
.120
.099-.141
S-.133
.104-.161
.124
.106-.142
.138
.116-.160
.114
.086-.142
OuluAll.133
.115-.150
.146
.124-.167
.150
.131-.169
.122
104-.140
T+S+.156
.094-.218
.149
.101-.198
.206
.122-.290
.131
.052-.210
S-.096
.042-.150
.207
.142-.272
.165
.112-.217
.097
.046-.148
T-S+.199
.138-.259
.140
.090-.190
.138
.092-.184
.115
.068-.162
S-.123
.065-.181
.158
.114-.201
.175
.107-.242
.056
.008-.103
WFinlandAll.028
.027-.029
.032
.030-.033
.030
.029-.031
.025
.024-.027
HelsinkiAll.047
.043-.051
.053
.048-.058
.050
.045-.054
.043
.039-.048
T+S+.052
.040-.064
.055
.046-.065
.056
.044-.068
.033
.018-.048
S-.044
.030-.057
.059
.047-.072
.055
.041-.069
.055
.044-.067
T-S+.051
.032-.070
.049
.036-.061
.049
.040-.058
.036
.028-.045
S-.051
.034-.067
.046
.034-.058
.048
.037-.058
.045
.025-.065
OuluAll.038
.029-.047
.045
.034-.057
.035
.027-.042
.038
.029-.047
T+S+
S-
.023
.005-.042
.039
.017-.060
.044
.014-.074
-
.035
.012-.058
.053
.018-.087
.015
.001-.029
.026
.002-.050
T-S+
S-
.062
.028-.096
.030
.006-.054
.042
.024-.061
.036
.013-.059
.030
.003-.058
.060
028-.091
.032
.010-.054
-

Table 4

Accelerating and decelerating periods of the equation of time and men's (M) and women's (W) suicide mortality

Daily mean of suicide mortality and confidence interval of the mean in aggregate over the years from 1969 to 2003 for men and women, during accelerating (X1, X2) and decelerating (Y1, Y2) periods of the equation of time in Finland, Helsinki and Oulu, and according to daily changes (+/-) in temperature (T) and sunshine hours(S) in Helsinki and Oulu.

X1: 11.02-14.05

Y1: 15.05-25.07

X2: 26.07-03.11

Y2: 04.11-10.2

AreaSelected daysPeriods of time of equation

D2A1D1A2
MFinlandAll.102
.098-.107
.125
.120-.130
.118
.112-.123
.107
.102-.111
HelsinkiAll.128
.121-.136
.146
.134-.158
.135
.122-.147
.130
.122-.139
T+S+.125
.103-.146
.142
.129-.154
.141
.123-.159
.128
.108-.148
S-.123
.102-.143
.142
.119-.164
.145
.121-.169
.116
.100-.131
T-S+.124
.111-.136
.162
.137-.187
.124
.108-.141
.134
.121-.146
S-.123
.103-.144
.147
.124-.171
.126
.110-.142
.141
.118-.164
OuluAll.125
.107-.144
.145
.123-.167
.148
.128-.168
.139
.119-.159
T+S+.099
.059-.139
.159
.123-.196
.137
.088-.185
.186
.121-.250
S-.105
.065-.145
.129
.080-.178
.177
.129-.225
.150
.104-.196
T-S+.140
.112-.168
.155
.103-.208
.146
.095-.197
.129
.090-.168
S-.109
.062-.157
.137
.097-.176
.122
.079-.165
.149
.091-.206
WFinlandAll.026
.024-.027
.032
.030-.034
.030
.028-.031
.028
.027-.030
HelsinkiAll.046
.042-.049
.051
.045-.056
.051
.046-.056
.048
.043-.053
T+S+.043
.034-.053
.058
.047-.069
.048
.039-.057
.056
.047-.065
S-.050
.033-.067
.047
.033-.062
.049
.038-.061
.052
.042-.062
T-S+.041
.034-.048
.051
.036-.066
.050
.040-.061
.048
.040-.056
S-.048
.039-.058
.057
.044-.069
.051
.040-.062
.048
.037-.059
OuluAll.036
.029-.044
.043
.032-.054
.041
.030-.053
.038
.031-.048
T+S+.037
.016-.059
.031
.013-.050
.036
.017-.054
.044
.019-.069
S-.033
.016-.049
.033
.013-.054
.058
.024-.092
.017
.005-.030
T-S+.045
.026-.063
.047
.020-.075
.040
.014-.066
.040
.022-.058
S-.025
.002-.048
.053
.021-.085
.041
.019-.064
.039
.020-.057

Table 5

Advanced and delayed periods of the equation of time and men's (M) and women's (W) suicide mortality

Daily mean of suicide mortality and confidence interval of the mean, in aggregate over the years from 1969 to 2003 for men and women, during advanced (A1, A2) and delayed (D1, D2) periods of the equation of time in Finland, Helsinki and Oulu, and according to daily changes (+/-) in temperature (T) and sunshine hours(S) in Helsinki and Oulu.

A1: 15.04-13.06

D1: 14.06-31.08

A2: 01.09-25.12

D2: 26.12-14.04

Finally, to rule out a potential confounder, we analyzed whether daylight saving time (hereafter DST) had any effect on the suicide mortality. DST was introduced in Finland 1981. From 1981 to 1994 DST lasted from the end of March until the end of September (hereafter DST1), and since 1995 DST has been in use from the end of March until the end of October, as in most parts of Europe (hereafter DST2). We calculated suicide mortality rates during one month period before, and after the transitions into and out of DST, separately for the years 1981 to 1994 (DST1) and years 1995 to 2003 (DST2), for which the suicide mortality rates of the corresponding periods during the years 1969 to 1980 were used as controls (Tables 6, 7, 8, 9,10, and 11).

Days1969-80*1981-2003

-1 m+1 m-1 m+1 m
MCImCImCImCI
FinlandAll.097.089-.106.111.102-.121.104.097-.111.117.110-.124
HelsinkiAll.114.096-.133.130.114-.146.135.120-.150.137.118-.155
T+S+.120.061-.180.160.100-.219.129.084-.173.140.102-.177
T+S-.100.054-.146.156.100-.212.128.084-.171.181.143-.220
T-S+.123.090-.156.102.067-.137.139.108-.171.142.100-.184
T-S-.144.044-.243.127.061-.194.180.114-.246.108.080-.136
OuluAll.113.064-.162.114.060-.168.121.092-.150.158.117-.199
T+S+------.110.042-.179
T+S-----.145.060-.229.146.055-.237
T-S+.123.037-.208.152.013-.291.104.038-.171.21.139-.280
T-S-----.065.002-.129.138.039-.237

Table 6

Men: Daily mean of suicide mortality, and switching into daylight saving time in spring.

Daily mean of suicide mortality during one month period before (-1 m), and after (+1 m) the switch into daylight saving time.

* = DST was not in use in Finland

m = daily mean of suicide mortality

CI = confidence interval of the mean

LocationDays1969-80 *1981-2003(DST1 + DST2)

-1 m+1 m-1 m+1 m
mCImCImCImCI
FinlandAll.024.020-.028.026.023-.029.027.024-.030.030.027-.033
HelsinkiAll.055.048-.062.043.031-.055.043.034-.052.049.040-.059
T+S+.042.014-.071.052.020-.083.047.019-.076.055.035-.076
T+S-.054.028-.080.031.010-.052.024.012-.037.046.030-.062
T-S+.061.041-.081.029.004-.053.040.022-.057.065.028-.101
T-S-.052.018-.087--.049.020-.079.044.024-.065
OuluAll.033.006-.059.048.016-.080.048.030-.066.030.009-.050
T+S+--------
T+S-----.053.013-.094--
T-S+----.067.018-.117--
T-S---------

Table 7

Women: Daily mean of suicide mortality and switching into daylight saving time in spring.

Daily mean of suicide mortality during one month period before (-1 m), and after (+1 m) the switch into daylight saving time.

* = DST was not in use in Finland

m = daily mean of suicide mortality

CI = confidence interval of the mean

LocationDays1969-80*1981-94 (DST1)

-1 m+1 m-1 m+1 m
mCImCImCImCI
FinlandAll.111.099-.122.101.094-.108.119.109-.128.120.112-.128
HelsinkiAll.141.106-.177.120.104-.137.139.125-.153.140.122-.158
T+S+.151.064-.238.115.078-.151.091.039-.143.163.107-.219
T+S-.156.076-.236.107.048-.166.124.087-.161.123.079-.167
T-S+.137.089-.185.132.083-.182.156.115-.197.144.107-.180
T-S-.138.087-.189.147.085-.208.184.125-.244.155.062-.248
OuluAll.114.060-.168.125.092-.158.239.165-.313.121.067-.175
T+S+----.324.113-.535--
T+S-.100.001-.200.107.002-.211.256.053-.458.110.000-.220
T-S+.189.084-.295.130.024-.237.182.060-.303.103.029-.176
T-S-----.267.142-.392.229.065-.393

Table 8

Men: Daily mean of suicide mortality, and switching away from daylight saving time in fall.

Daily mean of suicide mortality during one month period before (-1 m), and after (+1 m) the switch away daylight saving time.

* = DST was not in use in Finland

m = daily mean of suicide mortality

CI = confidence interval of the mean

LocationDays1969-80 *1981-94 (DST1)

-1 m+1 m-1 m+1 m
mCImCImCImCI
FinlandAll.028.025-.032.029.026-.033.029.024-.033.035.031-.039
HelsinkiAll.052.039-.064.048.033-.062.046.030-.061.064.049-.078
T+S+.071.045-.097.039.019-.058--.074.040-.108
S---.069.033-.104.049.015-.084.058.033-.083
T-S+.049.025-.073.055.021-.089.052.031-.073.067.038-.096
S-.070.022-.118.023.001-.046.032.005-.059.065.026-.103
OuluAll.033.011-.055.043.006-.081.020.001-.040.024.001-.047
T+S+--------
T+S---------
T-S+--------
T-S---------

Table 9

Women: Daily mean of suicide mortality, and switching away from daylight saving time in fall.

Daily mean of suicide mortality during one month period before (-1 m), and after (+1 m) the switch away daylight saving time.

* = DST was not in use in Finland

m = daily mean of suicide mortality

CI = confidence interval of the mean

Location Days1969-80*1995-2003 (DST2)

-1 m+1 m-1 m+1 m
mCImCImCImCI
FinlandAll.101.094-.108.101.093-.110.105.095-.115.097.088-.105
HelsinkiAll.126.108-.145.140.119-.161.118.079-.157.106.090-.121
T+S+.116.073-.159.181.078-.285.128.045-.212.080.033-.128
T+S-.134.085-.182.072.017-.127.117.059-.176.109.075-.142
T-S+.135.079-.191.177.105-.249.112.071-.153.093.054-.131
T-S-.152.072-.233.204.093-.314.099.035-.163.104.066-.142
OuluAll.131.089-.173.106.058-.154.145.096-.195.169.107-.230
T+S+--------
T+S-.104.003-.205--.200.069-.332--
T-S+.167.050-.284.085.001-.169----
T-S-----.148.006-.290--

Table 10

Men: Daily mean of suicide mortality, and switching away from daylight saving time in fall.

Daily mean of suicide mortality during one month period before (-1 m), and after (+1 m) the switch away daylight saving time.

* = DST was not in use in Finland

m = daily mean of suicide mortality

CI = confidence interval of the mean

Location Days1969-80 *1995-2003 (DST2)

-1 m+1 m-1 m+1 m
mCImCImCImCI
FinlandAll.029.026-.032.025.022-.029.032.026-.038.027.022-.032
HelsinkiAll.044.029-.058.042.033-.051.054.039-.070.035.026-.044
T+S+.032.011-.052.058.019-.097.104.050-.159.053.002-.104
T+S-.055.027-.083.074.036-.112.049.015-.083--
T-S+.046.015-.076.032.010-.054.034.002-.067.040.016-.065
T-S-.026.001-.051--.064.030-.099--
OuluAll.038.005-.072.032.010-.054.027.004-.051.051.012-.090
T+S+--------
T+S---------
T-S+--------
T-S---------

Table 11

Women: Daily mean of suicide mortality, and switching away from daylight saving time in fall.

Daily mean of suicide mortality during one month period before (-1 m), and after (+1 m) the switch away daylight saving time.

* = DST was not in use in Finland

m = daily mean of suicide mortality

CI = confidence interval of the mean

The 95% CIs of the daily mean values, controlled for the length of a period of study and the male and female population sizes in a region of study, were used to evaluate the statistical significance, so that if they did not overlap with each other, it was judged to indicate a marked statistical significance.

Results

In Finland, during the years 1969 to 2003, the daily mean of suicide mortality was at the highest, with a statistical significance, for both men (mean = .124, CI = .118-.129) and women (mean = .032, CI = .030-.033), during the period Y1, i.e. from May 14th to July 25th , as compared to the nationwide references (Table 4).

Local photoperiod

The highest daily mean of suicide mortality seem to have emerged later in Oulu compared with Helsinki, but only for men. Therefore, the results of men are reported here in more detail. The daily mean of suicide mortality was at the highest during the period Y1 in Helsinki (mean = .142, CI = .130-.154, Table 4), but during the period X2 i.e. from July 26th to November 3rd in Oulu (mean = .150, CI = .131-.169, Table 4). The same postponed pattern was found also when the time pattern of suicide mortality was evaluated by seasons. The daily mean of suicide mortality was highest in Helsinki during spring (mean = .138, CI = .128-.148), but during summer in Oulu (mean = .159, CI = .138-.180). Furthermore, a similar postponed pattern was seen from A1 (Helsinki) to D1 (Oulu) periods (Table 5). However, these results did not reach statistical significance.

Local daily weather changes

For men, the days with T+S+ seem to have had the highest daily mean of suicide mortality both in Helsinki, during the period Y1 (mean = .149, CI = .131-.167), and in Oulu, during the period X2 (mean = .206, CI = .122-.290), which were the most "dangerous" periods in these cities. However, when estimated by the 95% confidence intervals, there was no statistical difference in the variation of means of suicide mortality between the four types of weather changes. The daily mean of suicide mortality in Helsinki and Oulu, however, do exceed the nationwide daily means of suicide mortality (mean = .124 for Y1 in Finland, and mean = .112 for X2 in Finland), as do all the underlined values for different types of weather changes in Helsinki and Oulu compared with each period at issue in Tables 3, 4, and 5.

Daylight saving time

The use or timing of daylight saving time did not have a significant effect on the suicide mortality (Tables 6, 7, 8, 9, 10, and 11).

Discussion

Nationwide results

Our key finding of statistical significance demonstrates the increased suicide mortality on nationwide level in Finland during the period from May 14th to July 25th. This 76-day period covers symmetrically both sides of summer solstice (Figure 1). During this period there is only 1 to 4 hours of darkness during the night in Helsinki but no darkness at all in Oulu. For the photoperiod dynamics in these locations, see http://www.gaisma.com/en/location/helsinki.html and http://www.gaisma.com/en/location/oulu.html, whose sunrise and sunset calculations are based on the algorithms displayed on National Oceanic and Atmospheric Administration Surface Radiation Research Branch web site at http://esrl.noaa.gov/gmd/grad/solcalc/calcdetails.html, and e.g. for latitudes less than 72° north and south, accuracy is approximately one minute. It is of note here that the photoperiod in Finland due to its time zone is asymmetrical throughout the year, the period of daylight being always shorter for the a.m. hours than it is for the p.m. hours. This phenomenon influences the mechanisms that decode the duration of the melatonin signal in the melatonin-target tissues.

From the circadian-clock point of view, this period (May 14th to July 25th) is a challenge to alignment of the circadian rhythms with the sleep-wake cycle, and it resembles "the critical spring photoperiodic window" on intermediate to long days that has been characterized in sheep [37]. Some possible biological mechanisms for our current finding are briefly discussed in the following. The very long day (20 to 24 hours of daylight) might challenge the network within the circadian pacemaker that is comprised of the so-called evening and morning active cells, and that takes part in the seasonal adaptation in diurnal animals such as fruit flies [38,39] and sheep [37,40-42]. If this holds for humans as well, it is not known at the moment. If it does, it could mean that, when day lengths approximate fall and winter, the morning active cells dominate the circadian output, e.g. the sleep-wake behavior. This dominance of hierarchy is gradually transferred to the evening active cells as the days get longer in spring [38,39], the coincidence effect of the morning and evening active cells disappearing when the melatonin signal duration becomes insufficient to sensitize adenylate cyclase and to support a peak expression of the morning-active cells [37]. Interestingly, the speeding up of the evening active cells (e.g. by sunshine) makes the morning active cells run faster in long (summer) but not in short (winter) days [38]. In Finland, which is located at high to temperate latitudes with the light-dark transitions being most rapid around equinoxes, the asymmetrical photoperiod possibly favors the evening-active cells, and produces pronounced melatonin-dependent effects on gene expression during spring and fall. Whether such "locked morning active cells" contribute to the peak in deaths from suicide in spring in particular is not known. However, CRY2 and PER2 genetic variants, which might influence the evening and morning signals from the circadian pacemaker system, associate with depression vulnerability [43,44] in humans. Therefore, depressed individuals in particular might suffer from entrainment errors during periods that challenge the circadian pacemaker and predispose to circadian misalignment.

Local daily weather changes

The complexity of the circadian pacemaker system suggests that signals other than the seasonal changes in photoperiod, such as temporary variations in local weather conditions, are likely to play a role in the entrainment process [35,45]. Our finding of the later suicide peak in the northern area of study, Oulu-region, supports this. However, the daily mean of suicide mortality was almost as high also during the Y1 period in Oulu, as in Helsinki.

Hereafter we discuss the potential influence of daily weather changes for the suicide mortality in Helsinki and Oulu during the peak periods.

During the most dangerous periods, Y1 in Helsinki and X2 in Oulu, days with T+S+ seemed to be the worst for suicide mortality. From the circadian point of view the long daylight combined with the daily increase in ambient temperature and sunshine hours (T+S+) may have further phase advanced the circadian rhythm of the male suicide victims. An increase in sunshine hours and exposure to light may accelerate and advance the phase of the principal circadian clock, but an increase in ambient temperature and exposure to heat may have a similar effect [46]. The peaks of suicides have associated with ambient temperature in earlier studies [47-49], but so far, to our knowledge, the role of the circadian clocks has not been addressed.

Many lines of evidence suggest that abnormalities in the thermoregulatory processes are common among the depressed and therefore may cause or maintain the circadian misalignment. Patients with a major depressive episode tend to have elevated body temperature throughout the night, not during the day, and a phase advance of the circadian rhythm of core body temperature [18]. As hot nights might advance the phase of the circadian clock [50], and nocturnal body temperature during rapid-eye-movement sleep is influenced by hot, not cold, ambience [51], the dynamics of nocturnal temperatures might contribute to the advanced and rather fixed phase positions of circadian rhythms in major depressive episodes. In addition, sleep abnormalities, characteristically excessive rapid-eye-movement sleep at the cost of slow-wave sleep [17], are likely to give an abnormal (accelerating) feedback to the principal circadian pacemaker [26]. Further, during winter the duration of rapid-eye-movement sleep per night tends to increase [52], giving no support to deceleration and thereby favoring the desynchronization that may result in lowered mood and the subsequent increase in risk of suicide.

Daily fluctuations in temperature may play a part in the timing of suicides, either in combination with the long day length, or possibly also as a separate stressor. Studies concerning the over-activity in the functions of brown adipose tissue among the depressed [53] are most interesting in this respect, since the over-activity of brown adipose tissue may lead to reduced adaptation to rapid changes in ambient temperature that are typical during spring and fall. Once being activated, brown adipose tissue does not become quiescent easily [54], and if having been over-activated, it may through the thermoregulatory defect lead to disruption of the sleep-wake cycle and appetite control, and lead to early morning awakenings and loss of weight of the affected individual. Whether this kind of "vernalization failure" characterizes a suicide process and contributes to a mortality peak year after year is not known, but needs experimental data for analysis. However, in line with this background, for the Y1 period the daily mean of suicide mortality of men was at its lowest during the days of T-S- in Helsinki (mean = .124, CI = .106-.142, Table 4) and during the days of T-S+ in Oulu (mean = .140, CI = .090-.190, Table 4), suggesting that T- is a common nominator for the "safer" weather changes in both locations. T-S+ days were the "safest" also during the X2 period in Oulu. The daily decrease in temperature could therefore serve as a protective change during otherwise warm season. However, as the daily means did not differ significantly between the four types of weather changes, this is somewhat speculative thus far.

Limitations

Our limitation here is that we did not have the diagnostic information of the suicide victims, and that we demonstrate associations only, which do not necessarily tell anything about causality. Another limitation is that we did not have access to a suitable method, e.g. molecular-timetable methods [55] to be applied to a range of tissues, such as the brain and brown adipose tissue, from autopsy studies, to be able to analyze a mechanism of action and thereby to demonstrate a potential link between abnormalities in the circadian pacemaker system and death from suicide. On the other hand, our strengths include the nationwide sample of suicides for a long period of time, from a country with a high suicide mortality rate.

Conclusions

Our main findings here are that suicide mortality is higher during summer months and that daily changes in sunshine and ambient temperature are likely to modify the suicide mortality. Our findings presented herein now wait for tests by others in independent materials and is thus open to replication and the subsequent verification or falsification of the hypothesis. Some experimental data would be urgently needed for explanation of the mechanisms of action that take place in the brain of depressed patients and predispose them to suicide within those particular periods of time that we identified here. Suicide is a long process, whereas the timing of death from suicide appears far from random. In Finland from 1969 to2003 suicide mortality was elevated from May 15th to July 25th. This phenomenon should be considered also in clinical practice, since it bears implications for suicide prevention.

Competing interests

The authors declare that they have no competing interests.

Authors' contributions

Authors TP and KS designed the study and wrote the protocol. Author JL conceived and took part in designing the study. Authors LH and TP managed the literature searches and analyses and author LH wrote the first draft of the manuscript. All authors contributed to and approved the final manuscript.


Acknowledgements and funding

We thank Professor (Emeritus) of Mathematics Seppo Mustonen, PhD, University of Helsinki, Docent of Astronomy Heikki Oja, PhD, Almanac Office at the University of Helsinki, and the meteorologists Anneli Nordlund and Seppo Sarkkula at the Finnish Meteorological Institute, all in Helsinki, Finland, for their help in data processing.

The Finnish Cultural Foundation, Finnish National Graduate School for Clinical Investigation, and Finnish Graduate School of Psychiatry allocated scholarships (to LH) for this project but had no further role in study design.

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How to cite: Hiltunen, L, Suominen, K, Lönnqvist, J and Partonen, T 2011. Relationship between daylength and suicide in Finland. Journal of Circadian Rhythms 9:10, DOI: http://dx.doi.org/10.1186/1740-3391-9-10

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Published on 23 September 2011.

ISSN: 1740-3391 | Published by Ubiquity Press | Creative Commons License This work is licensed under a Creative Commons License.